Production and use of monoclonal anti-albumin antibodies to monitor the presence of bovine and porcine blood proteins in processed meat products

Abstract:
For determining added blood protein, known weights of processed (cooked) meat samples are extracted by boiling in 4 % (w/v) sodium dodecyl sulphate (SDS) and the soluble proteins collected by centrifugation. The resulting protein x containing SDS extract is then subject to separation on an SDS polyacrylamide gel, alongside “standards” (meat samples spiked with known amounts of serum and extracted the same way). The separated proteins are then transferred to nitrocellulose and probed using the species specific protein antibodies. The resulting bands are analysed using densitometry software and, using standard plots, an estimation made of added serum in a given sample.
PubYear:
2007
Keywords:
PAGE, serum
FundingBody:
Food Standards Agency (UK)
Contractor:
Nottingham Trent University
ProjCode:
Q01092
Associated:
Type:
Research: Laboratory Based
OpenAccess:
Yes
URL:
https://randd.defra.gov.uk/ProjectDetails?ProjectID=19128
Comments:
NA